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Patients with cystic fibrosis CF grow up in contact with a wide variety of health professionals, so it is hardly surprising that some wish to have a career in the health service. In an attempt to answer the question posed by the title, this editorial looks at three issues-the infection risks to the CF healthcare worker; the infection risks to the CF healthcare worker's patients; and the challenges of a health service career for an individual who already has to cope with the considerable demands of a CF therapy regimen. Patients and a healthcare environment pose a risk to all healthcare workers, but for workers with CF the risks may be greater. Box 1 lists the main organisms that are likely to be of concern. The fact is that cross-infection has become a nightmare for all patients with CF.

Probably the most hazardous environment of all is the CF unit-a miserable conclusion, because this is just the place where having a healthcare worker with CF could be of particular value. There is a dearth of published evidence in this whole area, and there are no data on the relative risks of, say, working in an intensive care unit, a burns unit, an infectious disease unit or a respiratory unit.

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Similarly there are no data on the value of measures to protect the CF healthcare worker, such as wearing masks, gowns or gloves. The risk to patients will depend on the nature of the organisms colonizing the CF healthcare worker's respiratory tract. Box 1 lists some of the more likely pathogens. If the CF individual has no cough, produces no sputum, and has no pathogenic bacteria in the respiratory tract, then there is no increased risk to patients. Alas, few individuals with CF have a completely symptomless respiratory tract.

Jan 1, - Just wondering if there is an app dedicated to this or other lifestyles. Got a friend interested in making one (a dating app) and we are exploring options to make it Online dating as a CF woman is a nightmare!: childfree Apr 2, - Bumble is basically Tinder for women and on a timer. Bumble is a free dating app that requires women to message first.

The large majority pose a threat to a greater or lesser degree, and regrettably there is no objective way to measure the hazard they present. Some situations are self-evidently very high risk-for example, a CF patient expectorating S. Many individuals with CF are highly motivated to work 78.

In one small study of 15 CF adolescents who were followed up, 10 were working in professional, semi-professional or clerical jobs, 3 were attending college and just 2 were unemployed because of CF 9. Not surprisingly, the most powerful predictors of being able to work are low disease severity and high self-esteem 9.

A patient with CF who is considering a health service career-or any other career for that matter-needs information on the duration and requirements of training, as well as the demands of the career. These factors must be considered against the need to maintain a therapeutic regimen which may include daily exercise, twice daily or more physiotherapy, various medications, and possibly admission to hospital.

A patient with CF considering a health service career must also give thought to the long term, and what will happen if and when his or her health deteriorates. This editorial paints a rather bleak and negative picture.

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The other side of the coin is that some people with CF have had immensely successful health service careers, and a diagnosis of CF should not be seen as a complete barrier to such a career.

The individual with CF who is contemplating a career in the health service needs to consider the issues of risk, and to discuss these with both a CF physician and a specialist in occupational health. For the reader who wishes to explore the subject in greater depth, it is one of several topics covered in this month's supplement to the JRSMbased on the latest Section of Paediatrics symposium on CF National Center for Biotechnology InformationU.

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J R Soc Med. Two weeks of intravenous antibiotic treatment failed to eradicate the infection in seven of eight patients. Three of the seven had infection with a mucoid Pseudomonas strain characteristic of chronic infection and therefore strongly suggestive of person-to-person spread at the camp.

All 22 stayed at the same hotel and participated in the same activities. After the camp all 22 patients had P.

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Importantly, these data show how the pattern of P. In our own experience in the late s, when Bcc infection was beginning to decimate CF clinics, two of our patients attended American summer camp holidays.

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Two and six months later, respectively, Bcc was isolated for the first time from these patients. One patient progressed to an accelerated decline over two years.

Jul 05,   People with CF are susceptible to infections and bugs which live in the lungs and because no two patients are exactly the same, they will be more likely to develop some infections over others. Two cystic fibrosis patients meeting each other in person will increase the risk of each one developing infections from the different bugs in each other. When There's More Than One Person With CF in the Same School Although cystic fibrosis is a rare disease, in some schools there may be more than one person with CF present. Germs are a major concern for people with CF, but there are steps you can take to help students and faculty with CF lower the risk of cross infection. Doctor answers on Symptoms, Diagnosis, Treatment, and More: Dr. Fields on why cant cystic fibrosis patients date each other: Patients with cystic fibrosis are highly susceptible to lung infections. As a result, if they spend a lot of time together, they can readily swap infections. This is one case where you should shun your parents' otherwise good advice on sharing. for topic: .

The other showed a precipitous deterioration and died 65 days later. Therefore, knowing that P. We know that increased separation of patients from each other limits the spread of P. When CF holiday camps are abandoned the cross infection rate falls markedly.

When There's More Than One Person With CF in the Same School

Over this five-year period, patients were treated according to a new protocol of three monthly elective courses of inpatient intravenous antibiotic therapy, with time spent in hospital increasing from two to eight weeks per year. Because the wards were near the outpatient clinics where all patients were seen, this new policy had increased the cross infection rate. As a response a protocol for cohort isolation was introduced inwith the following results: the annual incidence of intermittent P.

This proved that cohort isolation alone can delay chronic P. Following similar protocols in Leeds, the average age of onset of chronic P.

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One hundred and forty-five children presently have full care in our clinic. The need for patient segregation has been recently highlighted by the emergence of highly transmissible strains of P. The Liverpool adult centre has documented that these strains can infect patients who already have chronic P. The epidemic transmissible strain may then achieve dominance or co-dominance with the patient's previous strain.

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These patients had had no social contact outside the CF centre and all new infections were acquired by patients who had been recent inpatients. Cross infection within the unit had occurred. The same experience was reported in a paediatric centre in Australia.

Cf patients dating each other

The prevalence increased from 13 to If patients are allowed to mix freely, epidemic strains will spread across the CF community. In Australia, a genetically identical clone of P. Eighty percent of patients' room air samples were positive for the epidemic strain. Yet another reason to separate patients from each other is because epidemic strains are multi-resistant and show enhanced virulence.

Nine adult patients with the Liverpool epidemic strain were matched for age, lung function and BMI with nine patients with unique Pseudomonas strains. They also suffered a greater number of exacerbations.

Mucoid P. PGFE showed an identical pattern in eight of 27 infected children, including all five who died. In the month period following the study, children with the clonal strain were more likely to die from lung disease than those with other P. We must also remember the risk of infection with bacteria not commonly associated with respiratory infection in patients with CF, a risk enhanced by allowing patients to mix freely. Burkholderia dolosa25 Burkholderia pseudomallei 26 and Pandorea apista 27 have been associated with chronic infection, accelerated loss of lung function, and decreased survival.

Pandorea species may, like Bcc, present with bacteraemia. However, although some studies suggest that MRSA infection has only a minimal effect in CF despite its undisputed pathogenic role in non-CF patients, these studies are of short duration, uncontrolled and conducted on only a small numbers of patients. In Miall's study, ten infected children were compared to controls from one year before to one year after the onset of MRSA infection.

The MRSA group showed a non-significant trend towards decreased respiratory function, an increased requirement for intravenous antibiotic treatment in the year after the first isolate and a significantly worse height standard deviation score.

CF multidisciplinary team members who argue against segregation often refer to the support that families and patients give each other.

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However, our experience and the literature tell us that patients and families appreciate the need for segregation, deal with it well, and are concerned if they perceive it to be breached on any occasion. The majority of parents and patients are positive about segregation measures.

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Parents were aware of the positive and negative cts but concluded that segregation was necessary. In conclusion, there is overwhelming evidence that cross infection with a number of respiratory pathogens occurs in CF units when patients are allowed to mix with each other.


Affecting about 30, people in the United States and 70, people worldwide, cystic fibrosis is the most common lethal genetic disorder, says Mark Wylam, M. Fluid lines the lungs to help cilia hair-like protrusions sweep germs out of the airways to be swallowed or coughed up, explains Wylam.

Nov 15,   Resistance. Unfortunate experience with CF camps, dating, and support groups showed us that highly resistant bacteria (including pseudomonas aeruginosa, burkholderia cepacia, mrsa) were shared between tiendakiteboarding.com bacteria lead to declines in lung function and complicate treatment. Mar 14,   Shortly before my medical training, there were a lot of "CF camps" out there where children with CF could get together, bond, share their experiences with each other, learn about their disease, etc. They were great for the young patients' morale. Mar 15,   Men with cystic fibrosis are also born without a vas deferens, the tube that delivers sperm from the testicles to the penis. And at least two thirds of .

In people with cystic fibrosis, that layer is significantly reduced due to a gene mutation that causes a defect in a protein cystic fibrosis transmembrane regulator, or CFTR that moves salt in and out of cells. This causes the fluids in the lungs and other organs to be thick and sticky, so instead of moving things along, it plugs up tubes, ducts, and passageways. This traps germs, causing frequent, persistent infections.

People with cystic fibrosis may not have any symptoms for a long time, even as their lung function gradually decreases. These symptoms increase in frequency while the germs in the lungs become increasingly virulent and resistant to antibiotics. That can lead to frequent hospitalizations, weight loss, functional decline, and eventually respiratory failure, says Wylam.

Although there is controversy about how far one should take measures to prevent cross-infection-objective data are scarce-many units make strenuous efforts to keep CF patients apart from each other: gone are the outings for patients with CF to Alton Towers, the day trips to Blackpool, the CF holiday camps. But keeping patients with CF apart Cited by: 1. Feb 23,   Those of us who work in CF are compelled to discourage people with CF from socializing because of the risk of increased infection. There is a particularly nasty bacterium called B. Cepacia that is easily spread between CF patients. Having this bacteria could seriously decrease the life span of the CF patient. Jul 01,   CF multidisciplinary team members who argue against segregation often refer to the support that families and patients give each other. However, our experience and the literature tell us that patients and families appreciate the need for segregation, deal with it well, and are concerned if they perceive it to be breached on any tiendakiteboarding.com by: 8.

Men with cystic fibrosis are also born without a vas deferens, the tube that delivers sperm from the testicles to the penis. And at least two thirds of CF patients also have problems with their digestive system, says Wylam. Ducts in the pancreas can become blocked, reducing absorption of vitamins and nutrients and potentially leading to diabetes.

And bile ducts in the liver can also become clogged, causing scarring of the liver and cirrhosis.

Jennifer Taylor-Cousar, April 2020 - COVID-19 and Cystic Fibrosis

Having just one copy from one parent makes you a carrier without having the disease.

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